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Aerosol Evacuation Methods for Coronavirus in a Dental Clinic

Phase 4

Recruiting

Led By Aaron Glick, DDS, FAGD, FICOI, D.ABDSM

Research Sponsored by The University of Texas Health Science Center, Houston

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Pivotal Trial

Drug Has Already Been Approved

No Placebo-Only Group

Summary

This trial will help researchers understand how effective mouth rinses and evacuation units are in preventing the spread of germs during dental procedures that create aerosols (fine sprays of water and other liquids). The study will also help researchers understand the risks that dental practitioners face when performing these procedures.

Who is the study for?

This trial is for dental patients who are having their first procedure of the day, which involves prepping natural teeth and lasts at least an hour. It aims to assess aerosol risks in a dental clinic during procedures that generate aerosols.

What is being tested?

The study is testing how effective different methods like external evacuation devices (EED), extraoral vacuum aspirators (EVA), high volume evacuations (HVE), and hydrogen peroxide mouth rinses are at reducing airborne particles during dental treatments.

What are the potential side effects?

Potential side effects may include discomfort from using the evacuation devices or mouth rinse. Hydrogen peroxide can sometimes cause irritation or white patches inside the mouth if used frequently.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

Pivotal Trial

The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.

Drug Has Already Been Approved

The FDA has already approved this drug, and is just seeking more data.

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups

Experimental Treatment

Group I: High volume evacuation (HVE) suction only and hydrogen peroxideExperimental Treatment2 Interventions

Group II: HVE suction and extraoral vacuum aspirator (EVA) and hydrogen peroxideExperimental Treatment3 Interventions

Group III: HVE suction and external evacuation device (EED) and hydrogen peroxideExperimental Treatment3 Interventions

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Hydrogen Peroxide

2017

Completed Phase 3

~1640

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

The University of Texas Health Science Center, HoustonLead Sponsor

949 Previous Clinical Trials

344,975 Total Patients Enrolled

Aaron Glick, DDS, FAGD, FICOI, D.ABDSM5.04 ReviewsPrincipal Investigator - The University of Texas Health Science Center, Houston

The University of Texas Health Science Center, Houston

5Patient Review

I have had several positive experiences at Stephens and Gatewood, so I decided to return for a cavity filling. Dr. Glick was my dentist this time, and I was so pleased with his manner. He explained the procedure beforehand, which put me at ease, and then he did a great job with the filling itself. He was quick and thorough, and I would recommend him to anyone.

Claudia Ruiz Brisuela, DDSPrincipal InvestigatorThe University of Texas Health Science Center, Houston