← Back to Search

Other

Scalp Cooling for Chemotherapy-Induced Hair Loss

N/A

Recruiting

Led By Beth McLellan, MD

Research Sponsored by Montefiore Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patient will be starting >4 cycles of taxane-based chemotherapy treatment for curative intent after enrollment

Diagnosis of breast or non-small cell lung cancer (NSCLC) stage I-III

Must not have

Planned bone marrow ablation chemotherapy or skull irradiation

Past chemotherapy administration or administration of anthracyclines (doxorubicin)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to approximately 11 months (from the start to completion of chemotherapy)

Awards & highlights

No Placebo-Only Group

Summary

This trialis testing methods to improve scalp cooling efficacy in cancer patients with skin of color, to reduce chemotherapy-induced hair loss.

Who is the study for?

This trial is for adults over 18 with breast or non-small cell lung cancer at stages I-III, starting taxane-based chemo. It's specifically for those with curly (type 3) or kinky (type 4) hair who are generally active and can care for themselves. Excluded are individuals with other cancers, certain health conditions like severe anemia or diabetes, a history of migraines, scalp metastases, past specific chemotherapy treatments, or advanced-stage IV cancer.

What is being tested?

The study tests two hairstyling techniques to improve the effectiveness of scalp cooling in preventing hair loss from chemotherapy in patients of color: one using braids/cornrows/twists and another using water/conditioner emulsion. The goal is to enhance cap-to-scalp contact and assess long-term effects on hair preservation up to six months post-treatment.

What are the potential side effects?

While not explicitly stated in the provided information, potential side effects may include discomfort from cold during treatment sessions due to scalp cooling devices and possible headaches. Long-term side effects will be studied as part of this trial.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I will start a chemotherapy treatment with taxane for more than 4 cycles.

Select...

I have been diagnosed with early to mid-stage breast or lung cancer.

Select...

I can take care of myself but may struggle with hard physical activities.

Select...

I am older than 18 years.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I am scheduled for intense chemotherapy or radiation therapy targeting my skull.

Select...

I have previously received chemotherapy or drugs like doxorubicin.

Select...

I have a history of migraines, anorexia, severe anemia, uncontrolled diabetes, hepatitis, thyroid issues, cold urticaria, cold agglutinin disease, or scalp metastases.

Select...

I use hair weave/extensions and don't plan to remove them.

Select...

I do not have any other types of cancer, including blood cancers.

Select...

I have mild hair loss.

Select...

I have been diagnosed with stage IV breast cancer or non-small cell lung cancer.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to approximately 11 months (from the start to completion of chemotherapy)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to approximately 11 months (from the start to completion of chemotherapy)

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to approximately 11 months (from the start to completion of chemotherapy) for reporting.