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Genetic Testing Interventions for Cancer Risk (MiGHT Trial)
N/A
Waitlist Available
Led By Elena Stoffel, MD, MPH
Research Sponsored by University of Michigan Rogel Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months after enrollment/randomization
Awards & highlights
No Placebo-Only Group
Summary
This trial is testing whether two experimental interventions (a website and motivational phone calls) increase the likelihood of patients getting genetic testing recommended by medical guidelines, compared to receiving usual care.
Who is the study for?
This trial is for English-speaking adults in Michigan with a history of certain cancers (breast, ovarian, endometrial, colorectal, prostate or pancreatic) who haven't had genetic testing yet. They must have internet access and meet specific clinical criteria for genetic evaluation based on their cancer type and family history.
What is being tested?
The study compares three methods to see if they increase the likelihood of getting recommended genetic testing: a virtual genetics navigator website with tailored content; motivational interviewing calls by trained coaches; or usual care without these interventions.
What are the potential side effects?
Since this trial involves non-invasive interventions like educational resources and counseling calls rather than medications or medical procedures, there are no typical side effects associated with participation.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 6 months after enrollment/randomization
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months after enrollment/randomization
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Percentage of participants who complete clinical genetic testing at six months after randomization
Secondary study objectives
Barriers to genetic testing, for participants who completed genetic testing
Barriers to genetic testing, for participants who did not yet complete genetic testing
Motivators of genetic testing, for participants who completed genetic testing
+1 moreAwards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
3Treatment groups
Experimental Treatment
Active Control
Group I: Arm 3 - Motivational interviewing (MI)Experimental Treatment1 Intervention
Participants receive up to 2 phone calls from trained genetics health coaches who provide information about genetic testing and use motivational interviewing to encourage participants to seek out clinical genetic testing.
Group II: Arm 2 - Virtual genetics navigatorExperimental Treatment1 Intervention
Participants receive access to an online genetics tool, the virtual genetics navigator, to help learn why and how to seek out genetic testing for hereditary cancer syndromes.
Group III: Arm 1 - Usual care (UC)Active Control1 Intervention
Participants are provided with a link to the Michigan Department of Health and Human Services (MDHHS) informational website and are instructed to follow up with their oncology provider about genetic testing.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Motivational interviewing (MI)
2007
N/A
~400
Find a Location
Who is running the clinical trial?
University of Michigan Rogel Cancer CenterLead Sponsor
300 Previous Clinical Trials
20,404 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,958 Previous Clinical Trials
41,111,749 Total Patients Enrolled
Elena Stoffel, MD, MPHPrincipal InvestigatorUniversity of Michigan Rogel Cancer Center
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I was diagnosed with prostate cancer before 50, am of Ashkenazi Jewish descent, or have a close relative with ovarian, pancreatic, breast (diagnosed before 50), or male breast cancer.I have a personal or family history of breast cancer with specific conditions.I have a history or risk of cancer based on family history or personal health.I meet the criteria for a genetic test due to certain conditions.I have had genetic testing for cancer or have an appointment for it.
Research Study Groups:
This trial has the following groups:- Group 1: Arm 1 - Usual care (UC)
- Group 2: Arm 3 - Motivational interviewing (MI)
- Group 3: Arm 2 - Virtual genetics navigator
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.