← Back to Search

Accentuated eccentric loading + electromyostimulation for Head and Neck Cancers

N/A

Waitlist Available

Led By Gui Millet, PhD

Research Sponsored by University of Calgary

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline to after the 12-week intervention, at 6 month and 12 month follow up

Awards & highlights

No Placebo-Only Group

Summary

People who receive radiation therapy for head and neck cancer (HNC) can experience side-effects which include a significant loss in body mass and a loss of muscle mass (cancer cachexia). Some research has shown success in the use of generic (dynamic) resistance training interventions for patients affected by head and neck cancer. However, this approach could be optimized with the use of novel training methods.The primary aim of this research is to investigate the effect of conventional resistance training vs. an experimental intervention (electromyostimulation combined with accentuated eccentric loading) on muscle strength and muscle mass after radiation for HNC.

Eligible Conditions

Head and Neck Cancers

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline to after the 12-week intervention, at 6 month and 12 month follow up

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline to after the 12-week intervention, at 6 month and 12 month follow up

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to after the 12-week intervention, at 6 month and 12 month follow up for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Assessment of change in Muscle Cross-Sectional Area

Maximal Isometric Force in the Knee Extensors

Secondary study objectives

Assessment of change in the Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-Fatigue) Scale

Assessment of change in the Functional Assessment of Chronic Therapy - Head and Neck (FACT-H&N) Scale

Body mass index

+6 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Accentuated eccentric loading + electromyostimulationExperimental Treatment1 Intervention

This group will undertake a supervised 12-week intervention involving accentuated eccentric loading and electromyostimulation of the knee extensors, dynamic resistance training of lower limb antagonist and synergist muscles and upper limb dynamic resistance training.

Group II: Traditional resistance trainingActive Control1 Intervention

This group with undertake a supervised 12-week intervention involving volume matched dynamic resistance training of the knee extensors, and dynamic resistance training of lower limb antagonist and synergist muscles and upper limb dynamic resistance training.

Do I qualify?Apply below to find out