Trials in Boston, Massachusetts
Here are the top 10 medical studies for depression in Boston, Massachusetts
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Phase 3 Trials
Behavioural Intervention
Solriamfetol for Depression
Recruiting1 awardPhase 3
Boston, Massachusetts
This trial is testing solriamfetol, a medication that may help improve symptoms of depression. It targets adults with major depressive disorder (MDD) who do not have psychotic features. Solriamfetol works by affecting brain chemicals involved in mood regulation, potentially helping to improve mood and reduce depression symptoms.
NMRA-335140 for Depression
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial is testing a new medication called NMRA-335140 to see if it helps people with major depressive disorder. It includes participants who have no safety concerns. The medication aims to improve mood by affecting brain chemicals.
Psychedelic
Psilocybin for Treatment-Resistant Depression
Recruiting1 awardPhase 3
North Worcester, Massachusetts
This trial is testing a new medication called COMP360 to help people with severe depression that hasn't improved with other treatments. The study involves adults aged 18 and older. Researchers want to see if a single dose of COMP360 can reduce depression symptoms when given with psychological support.
Lumateperone for Major Depressive Disorder
Recruiting1 awardPhase 3
Methuen, Massachusetts
This trial is testing lumateperone, a medication that may help people with depression who haven't improved with other treatments. The study includes patients diagnosed with Major Depressive Disorder who haven't responded well to their current antidepressants. Lumateperone works by balancing brain chemicals that affect mood, potentially improving depressive symptoms.
Aticaprant + Antidepressant for Depression
Recruiting1 awardPhase 3
Boston, Massachusetts
This trial aims to see if aticaprant is effective in preventing the return of depression symptoms when added to antidepressant therapy in individuals with major depressive disorder who have already responded well to aticaprant treatment
Trials With No Placebo
Behavioral Intervention
Culturally Affirming Therapy for Depression and Anxiety
Recruiting1 award2 criteria
Chelsea, Massachusetts
This trial aims to see if a new therapy approach called Culturally Affirming Racial Equity (CARE) can improve therapy for diverse populations, even when the therapist and patient have different cultural backgrounds
Behavioural Intervention
Facilitated Transition to Primary Care for Postpartum
Recruiting1 award1 criteria
Boston, Massachusetts
This trial aims to improve postpartum primary care for new mothers by implementing a multi-component intervention during inpatient postpartum care. The goal is to increase primary care engagement, quality, and experience
NMRA-335140 for Depression
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial is testing a new medication called NMRA-335140 to see if it helps people with major depressive disorder. It includes participants who have no safety concerns. The medication aims to improve mood by affecting brain chemicals.
NMDA Receptor Antagonist
Ketamine + Esketamine for Depression
Recruiting5 awardsPhase 4
Boston, Massachusetts
This trialwill examine outcomes of patients with depression and suicidal ideation who receive IV ketamine & IN esketamine compared to a historical group. Patients will get 8 IV ketamine treatments, 13 esketamine visits & daily surveys. It will look at feasibility, tolerability & efficacy of the treatment.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.