Dyanavel Xr

Q: Is there a generic for DYANAVEL XR?

<p>While Dyanavel XR is an expensive drug used to treat <a href="https://www.withpower.com/clinical-trials/adhd">ADHD</a>, it is less popular than comparable drugs. There are no generic alternatives to Dyanavel XR currently.</p>

Narcolepsy, Depression, Attention Deficit Hyperactivity Disorder + 1 more

Treatment

2 FDA approvals

0 Active Studies for Dyanavel Xr

Treatment for

Narcolepsy

What is Dyanavel Xr

AmphetamineThe Generic name of this drug

Treatment SummaryAmphetamine is a highly-restricted controlled drug that was discovered over 100 years ago. It is made up of the chemical alpha-methylphenethylamine and is composed of two forms of isomers, dextro- and levo-isomers. It was originally used to reduce drug-induced anesthesia and produce arousal and insomnia, and it was approved by the FDA in 1976. During World War II, amphetamine was used to help soldiers stay awake, and after the war, much of the surplus ended up in the black market, leading to its abuse.

Adderallis the brand name

image of different drug pills on a surface

Dyanavel Xr Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Adderall

Amphetamine

1996

507

Approved as Treatment by the FDA

Amphetamine, also known as Adderall, is approved by the FDA for 2 uses which include Attention Deficit Hyperactivity Disorder and Narcolepsy .

Attention Deficit Hyperactivity Disorder

Used to treat Attention Deficit Hyperactivity Disorder (ADHD) in combination with Dextroamphetamine

Narcolepsy

Effectiveness

How Dyanavel Xr Affects PatientsAmphetamine affects the concentration of the neurotransmitters noradrenaline and dopamine in the brain in a dose and time-dependent way. It has been suggested to improve intelligence test scores and increase school performance, behavior, and demeanor for people with ADHD. However, it has also been linked to psychiatric dangers when misused, such as paranoia and depression.

How Dyanavel Xr works in the bodyAmphetamine has a similar structure to neurotransmitters like catecholamines. It works by attaching itself to sodium and chloride ions, which allow it to be taken in by the nerve terminals. It then competes with other neurotransmitters to get stored in the terminals, which causes them to be released into the synapse. This process is more effective in the d-isomer form of amphetamine. Amphetamine also works by limiting how much of the neurotransmitters are taken up and degraded by blocking the reuptake and monoamine oxidase enzymes. Additionally, it acts as a weak inhibitor of the mitochondrial enzyme MAO.

When to interrupt dosage

The proposed dosage of Dyanavel Xr is contingent upon the ascertained condition, like Disease, Chronic Pain and Attention Deficit Hyperactivity Disorder. The quantity of dosage can be found in the table below, in correlation with the mode of administration (e.g. Oral or Tablet - Oral).

Condition

Dosage

Administration

Attention Deficit Hyperactivity Disorder

, 5.0 mg, 10.0 mg, 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, 18.8 mg, 2.5 mg/mL, 3.125 mg, 9.375 mg, 6.25 mg, 1.875 mg, 2.5 mg, 7.5 mg, 1.25 mg, 3.75 mg, 15.0 mg, 1.25 mg/mL, 18.75 mg, 25.0 mg, 7.26 mg, 12.11 mg, 2.42 mg, 9.69 mg, 14.53 mg, 4.84 mg, 20.0 mg, 60.0 mg, 40.0 mg, 30.0 mg

Tablet - Oral, , Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Suspension, extended release - Oral, Suspension, extended release, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral

Chronic Pain

Narcolepsy

Depression

Warnings

Dyanavel Xr Contraindications

Condition

Risk Level

Notes

Agitation

Do Not Combine

advanced arteriosclerosis

Do Not Combine

Drug abuse

Do Not Combine

Hyperthyroidism

Do Not Combine

Hypertensive disease

Do Not Combine

symptomatic cardiovascular disease

Do Not Combine

Pulse Frequency

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Amphetamine may interact with Pulse Frequency

There are 20 known major drug interactions with Dyanavel Xr.

Common Dyanavel Xr Drug Interactions

Drug Name

Risk Level

Description

Clonidine

Major

The metabolism of Clonidine can be decreased when combined with Amphetamine.

Cyclophosphamide

Major

The metabolism of Cyclophosphamide can be decreased when combined with Amphetamine.

Dacomitinib

Major

The metabolism of Dacomitinib can be decreased when combined with Amphetamine.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Amphetamine.

Erlotinib

Major

The metabolism of Erlotinib can be decreased when combined with Amphetamine.

Dyanavel Xr Toxicity & Overdose RiskThe lethal dosage of amphetamine is 6.4mg/l. Overdosing can cause a range of symptoms, such as increased body temperature, shallow breathing, seizures, acidosis, kidney failure, liver damage, and loss of consciousness. There may also be neurological effects such as agitation, aggression, headache, and hallucinations. Cardiovascular issues such as abnormal heart rhythm, heart muscle problems, heart attack, and stroke may also occur. In the digestive system, overdose may cause abdominal pain, vomiting, diarrhea, cramping, lack of appetite, and bleeding. Animals studies have not found any evidence of cancer, chromosome damage, or infertility

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Dyanavel Xr Novel Uses: Which Conditions Have a Clinical Trial Featuring Dyanavel Xr?

Currently, there are 710 active trials evaluating the potential of Dyanavel Xr to combat Depression, Disease and Narcolepsy.

Condition

Clinical Trials

Trial Phases

Attention Deficit Hyperactivity Disorder

70 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1

Narcolepsy

4 Actively Recruiting

Phase 3, Phase 4, Phase 1

Chronic Pain

1 Actively Recruiting

Not Applicable

Depression

365 Actively Recruiting

Phase 1, Phase 2, Early Phase 1, Not Applicable, Phase 4, Phase 3

Dyanavel Xr Reviews: What are patients saying about Dyanavel Xr?

4.3Patient Review

11/6/2016

Dyanavel Xr for Attention Deficit Disorder with Hyperactivity

My daughter has Dysautonomia, as well as ADHD. Dyanavel has been a godsend for her; not only does it help with her ADHD symptoms, but it also acts as a vasoconstrictor, which has made a huge positive impact on my daughter's quality of life by minimizing her headaches and improving her GI system. The only problem we have is that the medication sticks to the pharmacy bottle and runs out days too soon, which is concerning.

3Patient Review

12/19/2017

Dyanavel Xr for Attention Deficit Disorder with Hyperactivity

At first, this medication was really effective. But now, I find that it makes me depressed. I'm not sure if it's the medication or if it's because taking it makes me feel like a failure.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about dyanavel xr

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does DYANAVEL XR last?

"The effects of DYANAVEL XR generally last for 13 hours after taking the medication."

Answered by AI

Is there a generic for DYANAVEL XR?

"While Dyanavel XR is an expensive drug used to treat ADHD, it is less popular than comparable drugs. There are no generic alternatives to Dyanavel XR currently."

Answered by AI

Is Dyanavel the same as Adderall?

"The three drugs mentioned are all manufactured by Neos Therapeutics and are used to treat ADHD. All three drugs are bioequivalent to Adderall XR."

Answered by AI

What is DYANAVEL XR used for?

"Amphetamine is a medication used to treat ADHD by changing the amounts of certain natural substances in the brain. It belongs to a class of drugs known as stimulants."

Answered by AI