← Back to Search
Antiseptic Solution
Antiseptic Skin Preparation for Joint Replacement Surgery (CLEANJoint Trial)
Barrie, Canada
N/A
Recruiting
Led By Raman Mundi, MD MSc FRCSC
Research Sponsored by Sunnybrook Health Sciences Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Scheduled to undergo aseptic revision total hip arthroplasty or total knee arthroplasty with exchange of at least one prosthetic component
Aged 18 years or older
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights
No Placebo-Only Group
Summary
This trial aims to compare two types of solutions that help remove harmful bacteria on the skin during surgery. The main goal is to see if these solutions can reduce the need for additional surgery or infections within a
See full description
Who is the study for?
This trial is for adults aged 18 or older who are scheduled to have revision surgery on a hip or knee replacement where at least one artificial joint part will be swapped out. It's not suitable for those with conditions that might interfere with the study.Check my eligibility
What is being tested?
The study compares two antiseptic solutions used during surgery: chlorhexidine gluconate-alcohol and povidone-iodine, to see which is better at preventing infections after hip or knee replacement revisions. Participants will be randomly assigned to a solution and surveyed twice post-surgery.See study design
What are the potential side effects?
Potential side effects may include skin reactions like irritation, redness, or rash from either chlorhexidine gluconate-alcohol or povidone-iodine solutions applied during surgery.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am scheduled for a hip or knee replacement revision.
show original
Select...
I am 18 years old or older.
show original
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 2 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Ability to collect complete data from participants
Ability to deliver intervention the patient is randomized to receive
Ability to link collected outcome data with ICES datasets
+3 moreAwards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Active Control
Group I: Chlorhexidine gluconate-alcohol solutionActive Control1 Intervention
Chlorhexidine gluconate-alcohol solution is a type of solution that has antiseptic properties, which means it helps to eliminate harmful bacteria on the skin at the time of surgery, and therefore, reduce the risk of infection.
Group II: Povidone-iodine solutionActive Control1 Intervention
Povidone-iodine solution is a type of solution that has antiseptic properties, which means it helps to eliminate harmful bacteria on the skin at the time of surgery, and therefore, reduce the risk of infection.
Find a Location
Closest Location:Royal Victoria Regional Health Centre· Barrie, Canada
Who is running the clinical trial?
Sunnybrook Health Sciences CentreLead Sponsor
690 Previous Clinical Trials
1,567,401 Total Patients Enrolled
Raman Mundi, MD MSc FRCSCPrincipal InvestigatorSunnybrook Health Sciences Centre
Raman Mundi, D MSc FRCSCPrincipal InvestigatorSunnybrook Health Sciences Centre