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Crohns Disease for Crohn's Disease (VOC Trial)

N/A
Recruiting
Led By Florian Rieder, MD
Research Sponsored by The Cleveland Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights
No Placebo-Only Group

Summary

Inflammatory Bowel Disease (IBD) are chronic diseases of the gut comprising Crohn's Disease (CD) and Ulcerative Colitis (UC). The symptoms of IBD consist of diarrhea, abdominal discomfort, weight loss, fatigue and rectal bleeding. However, symptoms and treatment vary between patients. Early management of IBD can lead to better response rates and decrease the risk of irreversible bowel damage and future disease complications such as surgeries. Current clinical tools for diagnosis and or assessing progression of IBD are either invasive (colonoscopy), have low patient acceptance (fecal calprotectin) or low accuracy (C-reactive protein). The purpose of this study is to collect clinical data and samples (including blood, breath and stool) donated by patients with IBD and patients with no IBD (controls) to facilitate research that may result in the development of new non-invasive methods of diagnosing IBD and understand the progression of the disease over time in order to better manage IBD patients.

Eligible Conditions
  • Crohn's Disease
  • Colitis
  • Inflammatory Bowel Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Other study objectives
Inflammatory Bowel Diseases

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Group I: Ulcerative ColitisExperimental Treatment1 Intervention
Potential participants will be identified based on their planned/scheduled endoscopy visit.
Group II: Non-IBDExperimental Treatment1 Intervention
Healthy subjects with no bowel disorders will be included as controls.
Group III: Crohns DiseaseExperimental Treatment1 Intervention
Potential participants will be identified based on their planned/scheduled endoscopy visit.

Find a Location

Who is running the clinical trial?

The Cleveland ClinicLead Sponsor
1,049 Previous Clinical Trials
1,370,455 Total Patients Enrolled
AbbVieIndustry Sponsor
1,017 Previous Clinical Trials
519,409 Total Patients Enrolled
Florian Rieder, MD5.01 ReviewsPrincipal Investigator - The Cleveland Clinic
The Cleveland Clinic
5Patient Review
Dr Rieder is extremely knowledgeable, thorough, and friendly. We really enjoy his company and would recommend him wholeheartedly.
~31 spots leftby Apr 2025