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Diagnostic Test

MRS Scan for Spinal Cord Lesions

N/A
Recruiting
Led By Rami Eldaya, MD
Research Sponsored by M.D. Anderson Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Volunteers: Adults > 18 years, healthy with no malignancy, demyelinating disease, back pain, degenerative disease, or spinal cord lesions, consent able patients
Be older than 18 years old
Must not have
Volunteers: Age < 18 years, pregnant or breastfeeding individuals, history of cancer, history of spinal cord lesions including malignant, demyelinating, or inflammatory, history of prior spinal surgery, history of implantable devices, history of MR claustrophobia, degenerative disease or spinal/back pain including myelopathy and radiculopathy, scoliosis
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion; an average of 1 year.
Awards & highlights
No Placebo-Only Group

Summary

"This trial aims to find out if magnetic resonance spectroscopy (MRS) can accurately detect spinal cord lesions."

Who is the study for?
This trial is for adults over 18 without spinal cord lesions, prior spinal surgery, implantable devices, MR claustrophobia, or degenerative back conditions. It includes those at high risk for LMD needing CNS radiation and healthy volunteers with no history of cancer or demyelinating diseases.
What is being tested?
The trial is testing the use of Magnetic Resonance Spectroscopy (MRS) to evaluate the spinal cord in patients at risk for leptomeningeal disease (LMD) and in healthy individuals to establish daily applicable parameters.
What are the potential side effects?
Since MRS is a non-invasive imaging technique similar to an MRI scan, side effects are minimal but may include discomfort from lying still during the procedure and loud noises from the machine.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am over 18, healthy, and have no history of cancer, nerve damage, back pain, or spinal issues.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I am over 18, not pregnant or breastfeeding, and have no history of cancer, spinal issues, surgeries, implants, MR claustrophobia, degenerative diseases, or scoliosis.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion; an average of 1 year.
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion; an average of 1 year. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Safety and Adverse Events (AEs)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: PatientsExperimental Treatment1 Intervention
Participants will be recruited from DI volunteer pool to implement MRS spine on.
Group II: Healthy VolunteersExperimental Treatment1 Intervention
Participants will be recruited from DI volunteer pool to implement MRS spine on.

Find a Location

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor
3,074 Previous Clinical Trials
1,803,334 Total Patients Enrolled
1 Trials studying Spinal Cord
60 Patients Enrolled for Spinal Cord
Rami Eldaya, MDPrincipal InvestigatorM.D. Anderson Cancer Center
~9 spots leftby Jul 2025