Your session is about to expire
What is Netromycin
NetilmicinThe Generic name of this drug
Treatment SummaryNetilmicin is a type of antibiotic used to kill certain bacteria. It works by interfering with the protein production of the bacteria, which prevents them from multiplying. Netilmicin is similar to gentamicin but has fewer side effects on the ears and kidneys. How exactly netilmicin kills the bacteria is not fully understood, but it is known to bind to the 30S ribosomal subunit and inhibit mRNA binding and tRNA site.
Netromycin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Netilmicin
0
Effectiveness
How Netromycin Affects PatientsNetilmicin is an antibiotic that is used to fight certain types of bacterial infections, especially those caused by Gram-negative bacteria such as Pseudomonas, Enterobacter, and Acinetobacter. It has been found to be effective against a variety of bacteria such as Escherichia coli, Klebsiella, Proteus, Citrobacter, and Neisseria gonorrhoea. When used in combination with other antibiotics, such as penicillin G or carbenicillin, it can have a synergistic effect, meaning it will be more effective than either one alone. However, net
How Netromycin works in the bodyNetilmicin works to stop bacteria from growing by interfering with the process of producing proteins. It binds to specific proteins and RNA molecules in the bacteria, blocking the decoding site responsible for translating the RNA into proteins. As a result, the wrong amino acids are inserted into the polypeptide, producing nonfunctional or toxic peptides. This prevents the bacteria from making proteins it needs to survive, stopping it from reproducing.
When to interrupt dosage
The proposed amount of Netromycin is contingent upon the diagnosed condition, including Obstetric infection, Biliary tract infection and Septic. The dosage depends on the method of delivery (e.g. Solution or Solution - Ophthalmic) featured in the accompanying table.Condition
Dosage
Administration
ocular bacterial infections
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Pneumonia
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Biliary tract infection
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Urinary Tract Infection (UTI)
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Communicable Diseases
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Gastrointestinal Tract Infections
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Obstetric infection
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Surgical Site Infections
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Urinary Tract Infections
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Conjunctivitis
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Eye Infections
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Uveitis
, 0.3 %, 100.0 mg/mL, 50.0 mg/mL
, Solution, Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Ophthalmic, Solution - Ophthalmic
Warnings
Netromycin ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Netilmicin may interact with Pulse Frequency
Common Netromycin Drug Interactions
Drug Name
Risk Level
Description
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Netilmicin is combined with Neomycin.
Tenofovir
Major
Netilmicin may increase the nephrotoxic activities of Tenofovir.
Tenofovir alafenamide
Major
Netilmicin may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir disoproxil
Major
Netilmicin may increase the nephrotoxic activities of Tenofovir disoproxil.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Netilmicin.
Netromycin Toxicity & Overdose RiskNetilmicin can cause kidney damage and hearing loss. The kidney damage is usually mild and reversible, and is less severe than other similar drugs. Hearing loss is caused by the drug accumulating in the inner ear and damaging the hair cells, and can cause symptoms such as vertigo, dizziness, loss of balance, and vomiting.
Netromycin Novel Uses: Which Conditions Have a Clinical Trial Featuring Netromycin?
58 active clinical trials are presently being conducted to assess the efficacy of Netromycin in treating Obstetric Infections, Pulmonary Infections and Surgical Site Infections.Condition
Clinical Trials
Trial Phases
Surgical Site Infections
15 Actively Recruiting
Not Applicable, Early Phase 1, Phase 3, Phase 4
Uveitis
0 Actively Recruiting
Conjunctivitis
0 Actively Recruiting
Urinary Tract Infection (UTI)
7 Actively Recruiting
Phase 1, Phase 3, Phase 4, Not Applicable
Biliary tract infection
0 Actively Recruiting
Obstetric infection
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Eye Infections
0 Actively Recruiting
Gastrointestinal Tract Infections
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Pneumonia
1 Actively Recruiting
Phase 1
Urinary Tract Infections
2 Actively Recruiting
Not Applicable
Patient Q&A Section about netromycin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is azithromycin an antibiotic?
"Azithromycin is a macrolide antibiotic that works by inhibiting the growth of bacteria. It cannot however treat viral infections such as colds or the flu."
Answered by AI
What is Netilmicin injection used for?
"Netilmicin is used to treat bacterial infections by preventing the synthesis of essential proteins required by bacteria to carry out vital functions."
Answered by AI
Is amikacin a strong antibiotic?
"Amikacin is mainly used to treat severe infections caused by multidrug-resistant, aerobic Gram-negative bacteria. This includes bacteria such as Pseudomonas, Acinetobacter, Enterobacter, E. coli, Proteus, Klebsiella, and Serratia. The only Gram-positive bacteria that amikacin has a strong effect on are Staphylococcus and Nocardia."
Answered by AI