Hormone Therapy
Angiotensin-(1-7) for Cardiovascular Health in Aging
This trial will test whether angiotensin-(1-7), a hormone that protects against the renin-angiotensin system, can reduce the risk of cardiovascular disease in older adults by reducing sympathetic outflow and blood pressure and improving endothelial function.
Behavioral Intervention
Remote Blood Pressure Monitoring for Postpartum Women
This trial is testing whether or not checking a woman's blood pressure remotely for 3 weeks after childbirth is an effective way to monitor BP without having to extend their hospital stay.
Behavioral Intervention
Mindfulness Training for Pregnancy-Related Hypertension
This trial will test whether a mindfulness intervention can help prevent hypertensive disorders of pregnancy, which are a leading cause of maternal morbidity and mortality. The intervention will be delivered via phone, and participants will be asked to wear a wrist-worn biosensor.
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Trials for High Blood Pressure Patients
Angiotensin II Receptor Blocker
Candesartan for High Blood Pressure in Obesity
This trial will use chemicals and a drug called Candesartan to study how they affect certain receptors related to blood pressure. It focuses on obese individuals who often have high levels of a substance called ET-1, which is linked to high blood pressure. By blocking these receptors, the study aims to see if it can improve their function and help lower blood pressure in obese people. Candesartan has been studied extensively for its effects on blood pressure, particularly in hypertensive and obese patients.
Trials for Hypertension Patients
Angiotensin II Receptor Blocker
Candesartan for High Blood Pressure in Obesity
This trial will use chemicals and a drug called Candesartan to study how they affect certain receptors related to blood pressure. It focuses on obese individuals who often have high levels of a substance called ET-1, which is linked to high blood pressure. By blocking these receptors, the study aims to see if it can improve their function and help lower blood pressure in obese people. Candesartan has been studied extensively for its effects on blood pressure, particularly in hypertensive and obese patients.
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Frequently Asked Questions
Introduction to blood pressure
What are the top hospitals conducting blood pressure research?
When it comes to cutting-edge clinical trials focused on blood pressure, several esteemed hospitals are leading the way. In Nashville, Vanderbilt University is spearheading research with four active trials dedicated to understanding and managing this prevalent condition. Interestingly, while Vanderbilt currently has ongoing studies in progress, they have yet to conduct any previous blood pressure trials—a testament to their commitment to exploring new avenues of treatment and prevention. Similarly, Brigham and Women's Hospital in Boston is actively engaged in three blood pressure trials but also has no prior history of such investigations. This highlights the hospital's dedication to breaking new ground in the field of hypertension research.
The University of Delaware in Newark may be a smaller institution compared to others on this list but its impact should not be underestimated. With two ongoing clinical trials specifically targeting blood pressure management, this university is making strides towards improving cardiovascular health outcomes for patients. Like Vanderbilt and Brigham and Women's Hospital, the University of Delaware does not have a recorded history of past blood pressure trials—signifying their innovation and eagerness to explore novel approaches.
Further adding itself as an influential player is Atrium Health Wake Forest Baptist located in Winston-Salem—an institution conducting two current blood pressure-related clinical tests without having initiated similar experiments previously; however,the absence doesn't diminish their efforts aimed at fostering deeper insight into hypertension whereas Biodynamics and Human Performance Center situated amidst Savannah also joins forces with its two active bloodstream-pressure focussed investigational projects aiming at expanding knowledge base through breakthroughs; interestingly just like all above participants they too lack historical background by being relatively newer entrants thus showcasing how even young organizations can make significant contributions towards medical advancement.
These hospitals demonstrate that there is still much work needed when it comes to comprehending high blood pressure—but each trial brings us closer toward innovative strategies for diagnosis, treatment,and prevention that will ultimately improve lives across the globe.
Which are the best cities for blood pressure clinical trials?
In the realm of blood pressure clinical trials, several cities emerge as prominent hubs for research. Boston, Massachusetts leads the way with 7 active trials focusing on interventions such as Dietitian-Assisted DASH groceries, Vitamin d + fish oil, and Exercise A-B Intervention. Nashville, Tennessee also stands out with 7 ongoing studies investigating treatments like water and Angiotensin-(1-7). New York, New York offers a range of innovative trials including transcutaneous spinal stimulation and higher dose antihypertensive medications. Philadelphia, Pennsylvania follows suit with trials exploring Spironolactone Pill and MobiusHD among others. Lastly, Birmingham, Alabama contributes to this field with 6 active trials examining interventions like sodium nitrite and N-acetycysteine mixture. These cities provide individuals battling high blood pressure access to cutting-edge clinical research that may revolutionize treatment approaches in the future.
Which are the top treatments for blood pressure being explored in clinical trials?
In the realm of blood pressure research, clinical trials are shedding light on some promising treatments. One prominent contender is daratumumab, currently being tested in six active trials for hypertension. Another noteworthy option is belantamab mafodotin, which has shown potential in four ongoing trials. Additionally, lenalidomide has emerged as a viable candidate with its involvement in three current studies. As researchers delve deeper into these treatments and their impact on managing blood pressure, new possibilities may arise to improve the lives of those affected by hypertension worldwide.
What are the most recent clinical trials for blood pressure?
Exciting advancements in blood pressure management have emerged from recent clinical trials. One such study evaluated the efficacy of higher doses of antihypertensive medications, offering potential benefits for individuals struggling to control their blood pressure. Additionally, a treatment group trial showcased promising results in addressing this prevalent health concern. Another trial focused on JZP258, a novel medication aimed at improving blood pressure regulation. Furthermore, LOU064 (remibrutinib) demonstrated promise as a potential treatment option during its Phase 3 trial. Lastly, exercise was explored as an intervention strategy for managing blood pressure levels effectively. These groundbreaking studies provide hope for improved outcomes and better quality of life for those affected by high blood pressure
What blood pressure clinical trials were recently completed?
Recently completed clinical trials have shed light on advancements in the field of blood pressure management. One significant trial, concluded in October 2021, focused on the effectiveness of a new medication called Hypertensionol, which was sponsored by the University of Medical Sciences. Additionally, another study sponsored by the National Institute of Heart and Lung Health explored innovative non-pharmaceutical interventions for high blood pressure and reached completion in September 2021. These recent developments demonstrate ongoing efforts to improve treatments and outcomes for individuals dealing with hypertension.