← Back to Search

Antisense Oligonucleotide

ARO-APOC3 for Dyslipidemias (MUIR Trial)

Phase 2
Waitlist Available
Research Sponsored by Arrowhead Pharmaceuticals
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years

Summary

This trial is testing a new drug to see if it is safe and effective. Participants will be randomly assigned to take the drug or a placebo, and will be monitored for 48 weeks. Those taking the placebo will be given the option to take the drug during an extension study.

Eligible Conditions
  • Mixed Dyslipidemias

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

5Treatment groups
Experimental Treatment
Placebo Group
Group I: ARO-APOC3 50 mg, Day 1 and Week 24Experimental Treatment1 Intervention
2 doses of ARO-APOC3 by subcutaneous (sc) injection
Group II: ARO-APOC3 50 mg, Day 1 and Week 12Experimental Treatment1 Intervention
2 doses of ARO-APOC3 by subcutaneous (sc) injection
Group III: ARO-APOC3 25 mg, Day 1 and Week 12Experimental Treatment1 Intervention
2 doses of ARO-APOC3 by subcutaneous (sc) injection
Group IV: ARO-APOC3 10 mg, Day 1 and Week 12Experimental Treatment1 Intervention
2 doses of ARO-APOC3 by subcutaneous (sc) injection
Group V: Placebo, Day 1 and Week 12 or Week 24Placebo Group1 Intervention
calculated volume to match active treatment by sc injection
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
ARO-APOC3
2019
Completed Phase 2
~700

Find a Location

Who is running the clinical trial?

Arrowhead PharmaceuticalsLead Sponsor
40 Previous Clinical Trials
4,614 Total Patients Enrolled
3 Trials studying Dyslipidemias
715 Patients Enrolled for Dyslipidemias
~86 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top