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Herbal Supplement

Milk Thistle for Gambling Addiction

Phase 2
Waitlist Available
Led By Jon E Grant, JD, MD, MPH
Research Sponsored by University of Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up once every two weeks for the 8 weeks of the study

Summary

This study is evaluating whether a natural substance may help reduce gambling urges.

Eligible Conditions
  • Gambling Addiction
  • Compulsive gambling

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~once every two weeks for the 8 weeks of the study
This trial's timeline: 3 weeks for screening, Varies for treatment, and once every two weeks for the 8 weeks of the study for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (PG-YBOCS)
Secondary study objectives
Clinical Global Impression-Improvement and Severity Scales (CGI-I and CGI-S)
Gambling Symptom Assessment Scale (G-SAS)
Hamilton Anxiety Rating Scale (HAM-A)
+4 more

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Milk ThistleActive Control1 Intervention
Capsule form, 150mg BID to 300mg BID
Group II: PlaceboPlacebo Group1 Intervention
Matched dosage of milk thistle daily.

Find a Location

Who is running the clinical trial?

University of ChicagoLead Sponsor
1,055 Previous Clinical Trials
760,654 Total Patients Enrolled
Jon E Grant, JD, MD, MPHPrincipal InvestigatorUniversity of Chicago
7 Previous Clinical Trials
834 Total Patients Enrolled
~5 spots leftby Nov 2025
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