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Behavioural Intervention

Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life with Chemotherapy-Induced Peripheral Neuropathy

N/A
Recruiting
Led By Ryan S D'Souza, MD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at baseline and 3, 6, and 12 months
Awards & highlights
No Placebo-Only Group

Summary

This study examines how spinal cord stimulation (SCS) affects pain level and quality of life in patients experiencing chemotherapy-induced peripheral neuropathy (CIPN). CIPN is a nerve problem and one of the potential side effects of chemotherapy that causes pain, numbness, tingling, swelling, or muscle weakness in different parts of the body. CIPN usually begins in the hands or feet and gets worse over time. SCS is a type of therapy that has proven to be effective in treating numerous non-malignant pain disorders including failed back surgery syndrome, refractory angina, limb ischemia, complex regional pain syndrome, and diabetic peripheral neuropathy. SCS may also be useful in patients with CIPN. This study evaluates how SCS affects pain and quality of life in patients undergoing spinal cord stimulation for CIPN.

Eligible Conditions
  • Cancer
  • Peripheral Neuropathy

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at baseline and 3, 6, and 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and at baseline and 3, 6, and 12 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Secondary study objectives
Adverse events
Health-related quality of life
Neuropathic pain severity
+4 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Observational (spinal cord stimulation, questionnaires)Experimental Treatment3 Interventions
Patients receiving spinal cord stimulation therapy complete questionnaires over 30 minutes at baseline and at 3, 6, and 12 months.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Spinal Cord Stimulation
2020
Completed Phase 4
~440

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH
13,957 Previous Clinical Trials
41,112,097 Total Patients Enrolled
14 Trials studying Peripheral Neuropathy
1,473 Patients Enrolled for Peripheral Neuropathy
Mayo ClinicLead Sponsor
3,362 Previous Clinical Trials
3,065,941 Total Patients Enrolled
6 Trials studying Peripheral Neuropathy
354 Patients Enrolled for Peripheral Neuropathy
Ryan S D'Souza, MDPrincipal InvestigatorMayo Clinic in Rochester
Ryan S D'SouzaPrincipal InvestigatorMayo Clinic in Rochester
~6 spots leftby Apr 2026
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