← Back to Search

Behavioral Intervention

THRIVE App for Alcohol Use and PTSD

N/A

Recruiting

Led By Emily Dworkin, PhD

Research Sponsored by University of Washington

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 1 month, 3 months, 6 months, 9 months, 1 year

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to determine the best version of the THRIVE app, which has been shown to help reduce alcohol misuse and posttraumatic stress in individuals who have experienced sexual assault. Participants in the study

Who is the study for?

This trial is for adults who can read and speak English, are students at a recruitment site, have recently experienced sexual assault, show signs of posttraumatic stress, own a private smartphone, live in the same state as the recruitment site most of the year, and report recent heavy drinking.

What is being tested?

The study tests different versions of the THRIVE app to see which one best reduces alcohol misuse and posttraumatic stress after sexual assault. Participants will be randomly assigned to use various features like activity scheduling or cognitive restructuring.

What are the potential side effects?

Since this intervention involves an app with psychological exercises and coaching calls rather than medication or medical procedures, side effects may include emotional discomfort or distress related to addressing traumatic experiences.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 1 month, 3 months, 6 months, 9 months, 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 1 month, 3 months, 6 months, 9 months, 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1 month, 3 months, 6 months, 9 months, 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Past-month alcohol problems

Past-month frequency of heavy episodic drinking

Past-month number of drinking days

+4 more

Secondary study objectives

Anxiety

Cannabis use & problems

Depression

+1 more

Other study objectives

Flourishing

Loneliness

Positive mental health

+1 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

8Treatment groups

Experimental Treatment

Active Control

Group I: Thoughts onlyExperimental Treatment2 Interventions

Participants are invited to use a version of the app for 21 days. Participants receive the Thoughts app module, but do not attend coaching calls.

Group II: Thoughts + CoachingExperimental Treatment3 Interventions

Participants are invited to use a version of the app for 21 days. Participants receive the Thoughts app module and attend coaching calls.

Group III: Coaching onlyExperimental Treatment2 Interventions

Participants are invited to use a version of the app for 21 days. Participants receive the non-core intervention components in the app and attend coaching calls.

Group IV: Activities, Thoughts, & CoachingExperimental Treatment4 Interventions

Participants are invited to use a version of the app for 21 days. Participants receive the Activities and Thoughts app modules and attend coaching calls.

Group V: Activities onlyExperimental Treatment2 Interventions

Participants are invited to use a version of the app for 21 days. Participants receive the Activities app module, but do not attend coaching calls.

Group VI: Activities + ThoughtsExperimental Treatment3 Interventions

Participants are invited to use a version of the app for 21 days. Participants receive the Activities and Thoughts app modules, but do not attend coaching calls.

Group VII: Activities + CoachingExperimental Treatment3 Interventions

Participants are invited to use a version of the app for 21 days. Participants receive the Activities app module and attend coaching calls.

Group VIII: No experimental componentsActive Control1 Intervention

Participants are invited to use a version of the app for 21 days. Participants receive only the non-core intervention components and do not attend coaching calls.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Cognitive restructuring

2014

N/A

~300

Coaching calls

2022

Completed Phase 2

~170