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SE after Seizure Action Plan for Epileptic Seizure

N/A
Waitlist Available
Led By Tobias Loddenkemper, MD
Research Sponsored by Boston Children's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 18 months
Awards & highlights

Summary

Data strongly suggests that aggressive and early treatment of status epilepticus (SE) is crucial for seizure abortion and prevention of long-term neurologic sequelae. We propose the creation of a seizure action plan, an intervention aimed to guide daily medication use, outline pre-hospital seizure first aid and rescue medication use, and direct emergency personnel in patients' individualized SE medication algorithm, with implementation through the electronic medical record. We hypothesize that the seizure action plan will promote daily medication adherence, increase use of home rescue mediation, and improve timeliness of AED (antiepileptic drug) delivery, length of hospital stay, and ICU admission rate in episodes of status epilepticus.

Eligible Conditions
  • Epileptic Seizure
  • Epilepsy

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~18 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 18 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Timeliness of AED administration
Secondary outcome measures
Adherence
Adverse events
Effect on patient/parent quality of life
+4 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: SE before Seizure Action PlanExperimental Treatment0 Interventions
450 patients with status epilepticus prior to seizure action plan initiation
Group II: SE after Seizure Action PlanExperimental Treatment1 Intervention
450 patients with status epilepticus after seizure action plan initiation

Find a Location

Who is running the clinical trial?

Boston Children's HospitalLead Sponsor
778 Previous Clinical Trials
5,580,724 Total Patients Enrolled
Tobias Loddenkemper, MDPrincipal InvestigatorBoston Children's Hospital
1 Previous Clinical Trials
17 Total Patients Enrolled
~28 spots leftby Sep 2025