Formoterol Fumarate

Proteinuria, Asthma, Itching + 16 more

Treatment

20 Active Studies for Formoterol Fumarate

Treatment for

Proteinuria

What is Formoterol Fumarate

Budesonide

The Generic name of this drug

Treatment Summary

Formoterol is a type of medication that is inhaled to treat asthma and COPD. It relaxes and widens the airways for up to 12 hours, making it easier to breathe. It works quickly (in 2-3 minutes) and is available as a single-entity product or in combination with other medications such as inhaled corticosteroids or long-acting muscarinic antagonists. It is prescribed to both relieve symptoms and for maintenance therapy.

Rhinocort

is the brand name

image of different drug pills on a surface

Formoterol Fumarate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Rhinocort

Budesonide

1994

134

Effectiveness

How Formoterol Fumarate Affects Patients

Formoterol is a drug that helps open up the airways in the lungs to make it easier to breathe. It begins working within 2-3 minutes and can last up to 12 hours. Taking formoterol without other asthma medications has been linked to an increased risk of death, so it should not be used without inhaled corticosteroids.

How Formoterol Fumarate works in the body

Formoterol is a medication designed to treat pulmonary diseases like COPD and asthma. It works by targeting beta2 receptors, which are mainly found in the airways of the lungs. Formoterol is 200 times more effective at targeting these receptors than the beta1 receptors found in the heart. When the beta2 receptors are activated, it triggers a reaction in the cells that increases levels of cAMP, which relaxes the airways and stops the release of inflammatory molecules.

When to interrupt dosage

The prescribed dosage of Formoterol Fumarate is determined by the diagnosed illness, including Bronchial Asthma, Bronchoconstriction and Asthma. The measure of dosage fluctuates depending on the technique of delivery (e.g. Solution - Respiratory (inhalation) or Aerosol) as featured in the table beneath.

Condition

Dosage

Administration

Crohn Disease

, 0.25 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.09 mg, 0.032 mg, 3.0 mg, 0.18 mg, 0.2 mg, 0.5 mg, 9.0 mg, 28.0 mg, 2.3 mg, 0.08 mg, 0.16 mg, 0.00008 mg/hour, 0.32 mg, 1.0 mg, 6.0 mg, 0.125 mg/mL, 4.0 mg, 0.064 mg/pump actuation, 0.4 mg/pump actuation, 0.1 mg/pump actuation, 2.0 mg/pump actuation, 0.2 mg/pump actuation, 0.182 mg/pump actuation

Respiratory (inhalation), Inhalant, , Inhalant - Respiratory (inhalation), Suspension, Suspension - Respiratory (inhalation), Aerosol, powder, Aerosol, powder - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Powder - Respiratory (inhalation), Powder, Aerosol, foam, Aerosol, foam - Rectal, Rectal, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, extended release, Tablet, extended release - Oral, Enema; Kit; Tablet, Enema; Kit; Tablet - Rectal, Capsule, extended release - Oral, Capsule, extended release, Capsule, coated pellets - Oral, Nasal; Respiratory (inhalation), Aerosol - Respiratory (inhalation), Aerosol, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Oral, Inhalant - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Powder, metered, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Cutaneous, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Kit, Powder, metered - Respiratory (inhalation), Powder - Nasal; Respiratory (inhalation), Aerosol, metered - Nasal, Capsule, coated pellets, Kit - Rectal, Capsule, delayed release - Oral, Capsule, delayed release, Patch - Cutaneous, Patch

Colitis, Collagenous

Proteinuria

Nasal Congestion

Asthma

Itching

Skin Diseases

Acute Coryza

Ulcerative Colitis

Rhinitis, Vasomotor

Nasal Polyps

Crohn's Disease

Eosinophilic Esophagitis

Hypersensitivity

IGA Glomerulonephritis

Sinusitis

Crohn Disease

maintenance therapy

Chronic Obstructive Pulmonary Disease

Warnings

Formoterol Fumarate has four contraindications and should not be taken concurrently with the conditions in the table below.

Formoterol Fumarate Contraindications

Condition

Risk Level

Notes

Asthma

Do Not Combine

Severe Hepatic Impairment

Do Not Combine

Status Asthmaticus

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Budesonide may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Budesonide may interact with Pulse Frequency

There are 20 known major drug interactions with Formoterol Fumarate.

Common Formoterol Fumarate Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with Abatacept.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Budesonide.

Abetimus

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with Abetimus.

Formoterol Fumarate Toxicity & Overdose Risk

The lowest toxic dose in rats of Formoterol has been found to be 3130mg/kg. Symptoms of an overdose include chest pain, high or low blood pressure, rapid heartbeat, nervousness, headache, shaking, seizures, and dry mouth. Patients may also experience low levels of potassium, high blood sugar, and an imbalance of acids in the blood. Treatment of an overdose should focus on relieving symptoms and monitoring the heart. A beta-blocker may be used to reduce any excessive stimulation of the adrenal glands.

image of a doctor in a lab doing drug, clinical research

Formoterol Fumarate Novel Uses: Which Conditions Have a Clinical Trial Featuring Formoterol Fumarate?

251 active clinical trials are currently underway to assess the potential of Formoterol Fumarate to mitigate Chronic Obstructive Pulmonary Disease (COPD), Moderate to Severe COPD and Chronic Obstructive Airway Disease.

Condition

Clinical Trials

Trial Phases

Asthma

87 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Not Applicable, Phase 2, Phase 3

Itching

3 Actively Recruiting

Phase 3, Not Applicable

Chronic Obstructive Pulmonary Disease

72 Actively Recruiting

Phase 3, Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4

Proteinuria

5 Actively Recruiting

Phase 2, Phase 3, Phase 4, Phase 1

IGA Glomerulonephritis

0 Actively Recruiting

Ulcerative Colitis

17 Actively Recruiting

Phase 3, Phase 2, Phase 1, Not Applicable, Phase 4

Sinusitis

0 Actively Recruiting

Crohn's Disease

53 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4, Early Phase 1

Hypersensitivity

1 Actively Recruiting

Phase 4

Colitis, Collagenous

0 Actively Recruiting

Skin Diseases

0 Actively Recruiting

maintenance therapy

0 Actively Recruiting

Rhinitis, Vasomotor

1 Actively Recruiting

Not Applicable

Eosinophilic Esophagitis

0 Actively Recruiting

Acute Coryza

0 Actively Recruiting

Crohn Disease

0 Actively Recruiting

Nasal Polyps

0 Actively Recruiting

Crohn Disease

0 Actively Recruiting

Nasal Congestion

0 Actively Recruiting

Formoterol Fumarate Reviews: What are patients saying about Formoterol Fumarate?

Patient Review

7/21/2009

Formoterol Fumarate for Prevention of Bronchospasms with Emphysema

Unfortunately, this medication caused me to have a grand mal seizure after just two months of use.

Patient Review

5/5/2011

Formoterol Fumarate for COPD with Chronic Bronchitis

We were very happy with this product and it's effectiveness. However, we cannot find it in Malta anymore, not even at our hospital.

Patient Review

8/17/2009

Formoterol Fumarate for Asthma

This treatment is highly effective.

Patient Review

12/28/2014

Formoterol Fumarate for Asthma

This drug has been a game-changer for me. I've had asthma all my life, and this medication has allowed me to live symptom-free for the past four years. I only need to take it once or twice a year now, which is a huge improvement over my previous quality of life.

Patient Review

10/26/2014

Formoterol Fumarate for Chronic Bronchitis

I had a really rough couple of days with bad coughing and wheezing, but this treatment cleared most of it up within 48 hours.

4.3

Patient Review

3/4/2013

Formoterol Fumarate for COPD with Chronic Bronchitis

I was having a lot of trouble breathing at night, but since using this product I've seen a drastic improvement. I don't have asthma, but this has still helped me a great deal.

3.3

Patient Review

9/20/2008

Formoterol Fumarate for Asthma

I had a severe skin rash reaction to symbicort, which has formoterol in it. I had to go see a dermatologist and use a steroid cream to get rid of it. Even after all of that, it took several weeks for the rash to completely heal.

2.3

Patient Review

3/26/2008

Formoterol Fumarate for Asthma

Patient Review

8/29/2012

Formoterol Fumarate for Emphysema

My doctor prescribed this to me because my inhaler wasn't helping with my shortness of breath, but I haven't noticed any real difference after taking it for a month.

Patient Review

11/26/2008

Formoterol Fumarate for Prevention of Bronchospasms with Emphysema

After developing a severe allergy to corticosteroids, I was switched to this medication. It controls my asthma effectively, but has some unfortunate side effects, like nausea and muscle cramping. The hard part is when I travel finding a refrigerator to keep it in.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about formoterol fumarate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is formoterol fumarate?

"Formoterol prevents or decreases wheezing and trouble breathing caused by asthma or ongoing lung disease."

Answered by AI

Is formoterol fumarate a steroid?

"Symbicort is a combination of a steroid and a long-acting bronchodilator. It is used to prevent bronchospasm in people with asthma or chronic obstructive pulmonary disease (COPD)."

Answered by AI

What is the brand name for formoterol fumarate?

"Perforomist is a prescription medicine used to treat the symptoms of Chronic Obstructive Pulmonary Disease."

Answered by AI

What kind of drug is formoterol?

"Formoterol is a medication that is inhaled through the mouth to open up the air passages in the lungs. This medication belongs to a class of drugs known as bronchodilators."

Answered by AI

Clinical Trials for Formoterol Fumarate

Have you considered Formoterol Fumarate clinical trials?

We made a collection of clinical trials featuring Formoterol Fumarate, we think they might fit your search criteria.

Have you considered Formoterol Fumarate clinical trials?

We made a collection of clinical trials featuring Formoterol Fumarate, we think they might fit your search criteria.

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MoblO2 for Chronic Lung Diseases

18+

All Sexes

Stanford, CA

Many patients with chronic lung disease (e.g., chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)) require supplemental oxygen (O2) at some point during their disease course. Practitioners prescribe O2 to patients with chronic lung disease in hopes of the following: 1) that it will limit desaturation events and combat breathlessness, thus preventing the frustratingly slow pace and numerous rest breaks patients are forced to adopt while doing even simple tasks; 2) that it will allow patients to be more active physically (perhaps increase their ability to exercise) and socially (perhaps leave the home more often); 3) that it will stave off putative complications of hypoxemia (e.g., cognitive dysfunction, pulmonary hypertension) and 4) that it will improve health-related quality of life (HRQL). However, despite the rationale for O2, and prescribers' good intentions, patients generally view O2 with frustration and fear - it threatens their HRQL, which is already impaired by having a condition that imposes itself on every aspect of their lives. Nasal cannulas and delivery devices call unwanted attention to patients when they are out in public. O2 users feel stigmatized and are often viewed as "smokers who get what they deserve, even if they never smoked a day in their lives" - or as disabled, sick or even infectious. O2 steals patients' independence, forcing them to plan their lives around it. The anxiety that patients and their caregivers experience around running out of oxygen, or not getting enough, immobilizes them and restricts participation in activities outside of the home. O2 disrupts the home environment, adding stress, and creating a burden for patients' caregiver-loved-ones who are often saddled with the responsibility of ensuring adequate equipment and supply of O2, and O2 is a constant reminder to patients they are living with a condition that could shorten their lives. O2 delivery equipment is typically heavy, unwieldy and intimidating. Different recommendations (e.g., insurance companies use 88% as a cut-off for SpO2, while many practitioners focus on 90%) make it confusing for patients, which almost certainly affects adherence. O2-requiringpatients are starving for things that can make their lives easier. An auto-adjusting O2 delivery device - one that automatically delivers the correct amount of O2 to maintain blood oxygen at desired, pre-set levels - would alleviate the need for patients to constantly (incessantly for many) monitor their peripheral oxygen saturation (SpO2) and adjust O2flow to meet the demands as exertion levels vary . The MoblO2 device is a battery-operated, light-weight, closed-loop O2 delivery device that houses a regulator (which attaches to compressed gas O2 tanks) and adjusts O2 flow to meet a pre-set blood oxygen level. A pulse oximeter is worn on the ear and transmits via Bluetooth to the device, which adjusts an internal valve to control flow on a second-to-second basis. The user sets the dial to the highest flow of O2 needed to meet the demands of activities they might perform (up to 15 liters per minute), and the device adjusts flow, up to the pre-set level to maintain SpO2 at a preset level (e.g., \> 90%). To conserve O2 supply in the tank - and to avoid over-oxygenation (which could be problematic for a small percentage of patients with the most severe COPD) - the MoblO2 begins to limit O2 flow at a SpO2 of 93%. The device can be manually over-ridden by the user, and should the battery run out - or the device fail for some unforeseen reason - the default position is valve open, so the users receive whatever flow of oxygen has been set on the dial. Given the substantial burdens of O2 on patients and their families, the hassles patients describe with having to monitor their SpO2 and repeatedly adjust the flow of O2 to meet their needs, patients and experts around the world have called for improvements in O2 delivery equipment. The MoblO2 is just such a remarkable improvement and a giant step forward in helping to ease the burdens of O2 on patients who require it. The purpose of this study is to investigate the effects of the MoblO2 O2 delivery device on a range of outcomes, including physical activity, amount (liters) O2 use; maintenance of adequate SpO2 levels; patient reported outcomes including symptoms, HRQL and satisfaction with the MoblO2 O2 device.

Waitlist Available

Has No Placebo

Stanford University

Jeff Swigris, DO, MS

Minnesota Health Solutions