← Back to Search

Local Anesthetic

Lidocaine Infusion for Chronic Pain in Children

Phase 3
Waitlist Available
Led By Lisa Isaac, MD
Research Sponsored by The Hospital for Sick Children
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline pain score (7 days prior to infusion) at 14 days after completion of infusion
Awards & highlights
Pivotal Trial
No Placebo-Only Group

Summary

This trial tests if lidocaine given through an IV can reduce long-term pain in children who haven't been helped by other treatments. Researchers will measure pain levels and daily activities to see if it works and is safe. Intravenous lidocaine has been studied for its pain-relieving effects in various conditions, including chronic pain and post-operative pain.

Eligible Conditions
  • Chronic Pain

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week prior to the infusion and at two and four weeks following the infusion.
This trial's timeline: 3 weeks for screening, Varies for treatment, and week prior to the infusion and at two and four weeks following the infusion. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Pain Score
Secondary study objectives
Adverse Events
Analgesic Requirement
Other study objectives
Pain Interference
School Attendance
Sleep

Awards & Highlights

Pivotal Trial
The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Lidocaine InfusionExperimental Treatment1 Intervention
All participants will receive intravenous lidocaine infusion of 42 mcg/kg/minute over 2 hours, for a total of 5 mg/kg. No bolus dose will be given.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Lidocaine Infusion
2010
Completed Phase 4
~410

Find a Location

Who is running the clinical trial?

The Hospital for Sick ChildrenLead Sponsor
710 Previous Clinical Trials
6,958,177 Total Patients Enrolled
8 Trials studying Chronic Pain
1,028 Patients Enrolled for Chronic Pain
Lisa Isaac, MDPrincipal InvestigatorThe Hospital for Sick Children

Media Library

Lidocaine (Local Anesthetic) Clinical Trial Eligibility Overview. Trial Name: NCT02983682 — Phase 3
Chronic Pain Research Study Groups: Lidocaine Infusion
Chronic Pain Clinical Trial 2023: Lidocaine Highlights & Side Effects. Trial Name: NCT02983682 — Phase 3
Lidocaine (Local Anesthetic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02983682 — Phase 3
~2 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top