Anti-metabolites
Genetically Modified T Cells + Decitabine for Ovarian Cancer
This trial studies a treatment combining enhanced immune cells and a drug to target difficult-to-treat ovarian and related cancers. The approach aims to improve the body's ability to find and destroy cancer cells.
Anti-metabolites
Berzosertib + Gemcitabine for Ovarian Cancer
This trial is testing a new drug, M6620, to see if it is more effective than standard treatment with gemcitabine hydrochloride alone in treating patients with ovarian, primary peritoneal, or fallopian tube cancer.
Popular Filters
Trials for Ovarian Cancer Patients
CAR T-cell Therapy
ICT Cell Therapy for Ovarian Cancer
This trial tests a new treatment using modified immune cells (AB-1015) for patients with ovarian cancer that didn't respond to standard treatments. The modified cells are designed to target and kill cancer cells. The goal is to find a safe dose and see if the treatment helps fight the cancer. Modified immune cells, such as those used in AB-1015, have shown good curative effects in treating ovarian cancer.
Monoclonal Antibodies
SGN-B7H4V for Advanced Cancers
This trial tests a new drug called SGN-B7H4V for safety and side effects in patients with advanced or metastatic solid tumors. It aims to find the right dosage and see if the drug can effectively treat their cancer.
Monoclonal Antibodies
Pembrolizumab + Paclitaxel +/- Bevacizumab for Ovarian Cancer
This trial is testing a new cancer treatment combining two drugs, pembrolizumab and paclitaxel, with or without bevacizumab. The goal is to see if this new combination can prolong the amount of time until the cancer progresses, compared to the current standard treatment.
Trials for SOC Patients
CAR T-cell Therapy
ICT Cell Therapy for Ovarian Cancer
This trial tests a new treatment using modified immune cells (AB-1015) for patients with ovarian cancer that didn't respond to standard treatments. The modified cells are designed to target and kill cancer cells. The goal is to find a safe dose and see if the treatment helps fight the cancer. Modified immune cells, such as those used in AB-1015, have shown good curative effects in treating ovarian cancer.
Monoclonal Antibodies
SGN-B7H4V for Advanced Cancers
This trial tests a new drug called SGN-B7H4V for safety and side effects in patients with advanced or metastatic solid tumors. It aims to find the right dosage and see if the drug can effectively treat their cancer.
Monoclonal Antibodies
Pembrolizumab + Paclitaxel +/- Bevacizumab for Ovarian Cancer
This trial is testing a new cancer treatment combining two drugs, pembrolizumab and paclitaxel, with or without bevacizumab. The goal is to see if this new combination can prolong the amount of time until the cancer progresses, compared to the current standard treatment.
Trials for BRCA1 Positive Patients
CAR T-cell Therapy
ICT Cell Therapy for Ovarian Cancer
This trial tests a new treatment using modified immune cells (AB-1015) for patients with ovarian cancer that didn't respond to standard treatments. The modified cells are designed to target and kill cancer cells. The goal is to find a safe dose and see if the treatment helps fight the cancer. Modified immune cells, such as those used in AB-1015, have shown good curative effects in treating ovarian cancer.
PARP Inhibitor
PARP Inhibitor + CTLA-4 Blockade for Ovarian Cancer
This trial is testing a combination of two drugs to treat ovarian cancer that is caused by a BRCA mutation. The drugs are a PARP inhibitor and a T cell checkpoint inhibitor. The trial is testing to see if this combination is safe and effective.
Chemotherapy
Chemotherapy + Pembrolizumab/Olaparib for Ovarian Cancer
This trial is testing a new combination of drugs to treat ovarian cancer. The new combination is pembrolizumab, carboplatin/paclitaxel, and maintenance olaparib. The hypothesis is that this new combination will be better than just carboplatin/paclitaxel at treating ovarian cancer.
PARP Inhibitor
Tremelimumab + Olaparib for Recurrent Ovarian Cancer
This trial is testing olaparib, a PARP inhibitor, with and without tremelimumab, an immunotherapy drug, to see if they are effective in treating patients with ovarian, fallopian tube, or peritoneal cancer that has returned.
Trials for BRCA2 Positive Patients
CAR T-cell Therapy
ICT Cell Therapy for Ovarian Cancer
This trial tests a new treatment using modified immune cells (AB-1015) for patients with ovarian cancer that didn't respond to standard treatments. The modified cells are designed to target and kill cancer cells. The goal is to find a safe dose and see if the treatment helps fight the cancer. Modified immune cells, such as those used in AB-1015, have shown good curative effects in treating ovarian cancer.
PARP Inhibitor
PARP Inhibitor + CTLA-4 Blockade for Ovarian Cancer
This trial is testing a combination of two drugs to treat ovarian cancer that is caused by a BRCA mutation. The drugs are a PARP inhibitor and a T cell checkpoint inhibitor. The trial is testing to see if this combination is safe and effective.
PARP Inhibitor
Tremelimumab + Olaparib for Recurrent Ovarian Cancer
This trial is testing olaparib, a PARP inhibitor, with and without tremelimumab, an immunotherapy drug, to see if they are effective in treating patients with ovarian, fallopian tube, or peritoneal cancer that has returned.
PARP Inhibitor
ZEN003694 + Talazoparib for Ovarian Cancer
This trial is testing a combination of two oral drugs, ZEN003694 and talazoparib, in patients with recurrent ovarian, fallopian tube, or primary peritoneal cancer. ZEN003694 helps stop cancer cells from growing, while talazoparib blocks an enzyme that cancer cells need to repair themselves. The goal is to see how well these drugs work together in this specific group of patients.
Phase 3 Trials
Corticosteroid
Relacorilant + Nab-Paclitaxel for Ovarian Cancer
This trial tests a new combination of two drugs for ovarian cancer patients who have no other treatment options left. The combination includes a drug that may make chemotherapy more effective and a chemotherapy drug that has been used in various cancer treatments. The goal is to see if this combination can help patients live longer without their disease getting worse.
Monoclonal Antibodies
Pembrolizumab + Paclitaxel +/- Bevacizumab for Ovarian Cancer
This trial is testing a new cancer treatment combining two drugs, pembrolizumab and paclitaxel, with or without bevacizumab. The goal is to see if this new combination can prolong the amount of time until the cancer progresses, compared to the current standard treatment.
Cancer Vaccine
Oregovomab + Chemo for Advanced Ovarian Cancer
This trial tests if oregovomab, an IV medication, can help treat advanced ovarian cancer when used with standard chemotherapy. It targets patients who have had surgery to remove tumors and aims to boost the immune system to fight cancer cells more effectively. Oregovomab has been previously tested in advanced ovarian cancer but did not improve outcomes.
Alkylating agents
Chemotherapy +/− Bevacizumab for Ovarian Cancer
This trial is studying carboplatin, paclitaxel, and gemcitabine hydrochloride given together with or without bevacizumab after surgery to treat patients with ovarian, epithelial, primary peritoneal, or fallopian tube cancer.
Trials With No Placebo
CAR T-cell Therapy
ICT Cell Therapy for Ovarian Cancer
This trial tests a new treatment using modified immune cells (AB-1015) for patients with ovarian cancer that didn't respond to standard treatments. The modified cells are designed to target and kill cancer cells. The goal is to find a safe dose and see if the treatment helps fight the cancer. Modified immune cells, such as those used in AB-1015, have shown good curative effects in treating ovarian cancer.
Corticosteroid
Relacorilant + Nab-Paclitaxel for Ovarian Cancer
This trial tests a new combination of two drugs for ovarian cancer patients who have no other treatment options left. The combination includes a drug that may make chemotherapy more effective and a chemotherapy drug that has been used in various cancer treatments. The goal is to see if this combination can help patients live longer without their disease getting worse.
Monoclonal Antibodies
SGN-B7H4V for Advanced Cancers
This trial tests a new drug called SGN-B7H4V for safety and side effects in patients with advanced or metastatic solid tumors. It aims to find the right dosage and see if the drug can effectively treat their cancer.
View More Related Trials
Frequently Asked Questions
Introduction to fallopian tube cancer
What are the top hospitals conducting fallopian tube cancer research?
Efforts to combat fallopian tube cancer, a rare and often overlooked form of gynecological cancer, are being spearheaded by top hospitals across the United States. In Houston's M D Anderson Cancer Center, researchers are currently engaged in seven active clinical trials focused specifically on this disease. With an impressive track record of 32 completed fallopian tube cancer trials since their first recorded study in 2002, this renowned institution is at the forefront of exploring innovative treatment options for patients. Similarly committed to advancing knowledge about this condition is the University of Colorado Hospital in Aurora. Their six ongoing trials and 15 previous studies conducted since initiating research in 2005 demonstrate their dedication to finding breakthroughs for fallopian tube cancer.
On the East Coast, Beebe Medical Center in Lewes has prioritized tackling this lesser-known form of cancer with five active clinical trials and a history that includes recording its first trial on fallopian tube cancer back in 2005 together with fifteen other investigations carried out afterward.Having made significant contributions to understanding and treating various diseases over its storied existence, Mayo Clinic extends its reach into Arizona's Scottsdale where they have initiated five current clinical tests while already accomplishing twelve previously executed experiments from starting pioneering investigation back until2005.Meanwhile,the Mayo Clinic branch located in Jacksonville Florida has also embarked onto these efforts; engaging themselves into five existing trials related towards such cases having successfully concluded ten others within sixteen years
Despite being relatively uncommon compared to other gynecological cancers like ovarian or uterine cancers,fallopian tube cancer still poses significant challenges as it often goes undiagnosed until later stages due to vague symptoms.Nonetheless,the unwavering commitment displayed by these leading medical institutions across different regions brings hope not only for those affected but also serves as inspiration pushing forward our collective fight against elusive forms of cancers worldwide
Which are the best cities for fallopian tube cancer clinical trials?
When it comes to fallopian tube cancer clinical trials, several cities emerge as prominent hubs for research and development. Denver, Colorado leads the way with 29 active trials focusing on treatments like Bevacizumab and Nivolumab, as well as Quality-of-Life Assessment. Los Angeles, California follows closely behind with 24 ongoing studies investigating different treatment approaches and assessing quality of life in patients. Boston also plays a significant role in this field, hosting 18 active trials that explore options such as Gemcitabine and Cediranib Maleate. Houston, Texas and Aurora, Colorado both contribute to the advancement of knowledge through their respective 17 active trials studying various interventions. These cities offer individuals diagnosed with fallopian tube cancer access to cutting-edge clinical trials that may improve outcomes and enhance overall quality of life.
Which are the top treatments for fallopian tube cancer being explored in clinical trials?
Clinical trials are paving the way for advancements in treating fallopian tube cancer. Prominent among these trials are several top treatments that hold promise for patients:
- Pembrolizumab: Currently being explored in two active clinical trials, with a total of 24 all-time trials dedicated to fallopian tube cancer since its introduction in 2015.
- Bevacizumab: Also showing potential, this treatment is being investigated in two ongoing trials and has accumulated a substantial 47 all-time clinical trials since its listing in 2005.
- Paclitaxel: Another contender, paclitaxel is currently under investigation in two active clinical trials and boasts an impressive history of 77 all-time fallopian tube cancer studies since it was first listed back in 2002.
- Quality-of-Life Assessment: Recognizing the importance of holistic care, researchers have included quality-of-life assessments as part of their studies. This element has been incorporated into two current clinical trials and has garnered attention through its inclusion in 22 all-time fallopian tube cancer research projects starting from 2005. These diverse approaches showcase the dedication to finding effective treatments while considering patients' well-being throughout their journey towards recovery.
What are the most recent clinical trials for fallopian tube cancer?
Exciting advancements in clinical trials offer hope for those fighting fallopian tube cancer. One of the most recent trials, MORAb-202, is currently in Phase 2 and shows potential as a treatment option. Additionally, IMGN151 Open Label is being investigated in Phase 1 for its efficacy against this type of cancer. PRO1184 has entered both Phase 1 and Phase 2 studies to assess its impact on fallopian tube cancer. AB-1015 is another promising drug under investigation during its Phase 1 trial period. Lastly, olvimulogene nanivacirepvec has reached Phase 3 and holds promise as an effective treatment option for patients battling fallopian tube cancer. These ongoing trials provide renewed optimism to individuals facing this challenging disease.
What fallopian tube cancer clinical trials were recently completed?
Several recent clinical trials have made significant progress in the field of fallopian tube cancer research. Notably, a trial conducted by pharmaand GmbH concluded in March 2021, focusing on Rucaparib as a potential treatment option. Northwestern University also completed a trial investigating Irinotecan Sucrosofate during the same month. In addition, Celldex Therapeutics carried out a study exploring CDX-527, which finished in August 2020. These advancements underscore the dedication of researchers and provide hope for patients battling this form of cancer.